中心概况Overview of the center

专家介绍

蒋宏峰

2021-12-28

3-1. 教育经历

2001-2007,北京大学生理学与病理生理学系,理学博士

1995-2000,苏州大学临床医学系,医学士

3-2. 工作经历

2017.03 – 现在首都医科大学附属北京安贞医院,教授

2012.06 – 2017.07,哥伦比亚大学医学中心,副研究员 Associate Research Scientist

2007.09 – 2011.08,哥伦比亚大学医学中心博士后研究员 Post-Doctoral Research Scientist

3-3. 发表论文和专利

1. Bai R, Chang Y, Saleem A, Wu F, Tian L, Zhang S, Li Y, Ma S, Dong T, Guo T, Jiang Y, You Y, Lu WJ, Jiang HF*, Lan F*. Ascorbic acid can promote the generation and expansion of neuroepithelial-like stem cells derived from hiPS/ES cells under chemically defined conditions through promoting collagen synthesis. Stem Cell Res Ther. 2021 Jan 9;12(1):48. (IF 6.8)

2. Liu T, Zhang S, Huang C, Ma S, Bai R, Li Y, Chang Y, Hang C, Saleem A, Dong T, Guo T, Jiang Y, Lu W, Zhang L, Jianwen L, Jiang H*, Lan F*. Microscale grooves regulate maturation development of hPSC-CMs by the transient receptor potential channels (TRP channels). J Cell Mol Med. 2021 Apr;25(7):3469-3483. (IF 5.3)

3. Chang Y, Li YN, Bai R, Wu F, Ma S, Saleem A, Zhang S, Jiang Y, Dong T, Guo T, Hang C, Lu WJ, Jiang H*, Lan F*. hERG-deficient human embryonic stem cell-derived cardiomyocytes for modelling QT prolongation. Stem Cell Res Ther. 2021 May 7;12(1):278. (IF 6.8)

4. Dong T, Zhang S, Chang Y, Bai R, Jiang Y, Ma S, Li Y, Jiang HF*, Lu WJ*. (2021) The establishment of a homozygous SNTA knockout human embryonic stem cell line (WAe009-A-50) using the CRISPR/Cas9 system. Stem Cell Res. 2021 Mar;51:102196. (IF 4.5)

5. Liu M, Yan M, Lv H, Wang B, Lv X, Zhang H, Xiang S, Du J, Liu T, Tian Y, Zhang X, Zhou F, Cheng T, Zhu Y, Jiang H*, Cao Y*, Ai D*. Macrophage K63-Linked Ubiquitination of YAP Promotes Its Nuclear Localization and Exacerbates Atherosclerosis. Cell Rep. 2020 Aug 4;32(5):107990. (IF 9.4)

6. Yan M, Cai WB, Hua T, Cheng Q, Ai D, Jiang HF*, Zhang X*. Lipidomics reveals the dynamics of lipid profile altered by omega-3 polyunsaturated fatty acid supplementation in healthy people. Clin Exp Pharmacol Physiol. 2020 Jul;47(7):1134-1144. (IF 2.6)

3-4. 承担课题

1京津冀基础研究合作专项,腹主动脉瘤代谢分型和诊治的精准医学研究,2019/10-2022/09,20万,在研,北京地区负责人。

2)国家自然科学基金,IL-1β激活巨噬细胞TRAF6-YAP通路促进动脉粥样硬化的发生及其机制研究,2020/01-2023/1255万,在研,项目负责人。