中心概况Overview of the center

专家介绍

刘旭霞

2021-12-28

3-1. 教育经历:

1997-2002,山东泰山医学院,临床医学,本科

2002-2005,首都医科大学,生理学,硕士

2005-2008,首都医科大学,内科学(心血管病),博士

3-2. 工作经历: 

2008-2010,阜外心血管病医院,博士后

2010-2016,首都医科大学附属北京安贞医院/北京市心肺血管疾病研究所,助理研究员

2016-至今,首都医科大学附属北京安贞医院/北京市心肺血管疾病研究所,副研究员

3-3. 主持或参加科研项目(课题)及人才计划项目情况:

1. 国家自然科学基金中加合作项目《欧洲和亚洲人群主动脉瓣钙化狭窄的遗传基础》(2019/01-2021/12,参与

2. 北京自然科学基金面上项目,7162032,利用患者特异的诱导多潜能干细胞研究扩张型心肌病猝死家系,2016/01-2018/12,主持

3. 国家自然科学基金青年项目,81401780,糖皮质激素通过调控成纤维/脂肪祖细胞的分化导致2型糖尿病小鼠骨骼肌内脂肪沉积的机制研究,2015/01-2017/12,参与

4. 国家自然科学基金青年项目,81300074,利用外显子捕获测序技术鉴定肥厚型心肌病新致病突变的研究,2014/01-2016/12,主持

5. 国家自然科学基金青年项目,81100144,趋化因子配体16CXCL16)导致心梗后炎症及心脏损伤的机制研究,2012/01-2015/12,参与

3-4.代表性论著

(1) Zheng S#, Piao C, Liu Y, Liu X, Liu T, Zhang X, Ren J, Liu Y, Zhu B, Du J*. Glycan Biosynthesis Ability of Gut Microbiota Increased in Primary Hypertension Patients Taking Antihypertension Medications and Potentially Promoted by Macrophage-Adenosine Monophosphate-Activated Protein Kinase.Front Microbiol. 2021 Nov 4;12:719599.

(2) Piao CZhu YZhang CXi XLiu XZheng SLi XGuo JJia LNakanishi TCai TGu HDu JIdentification of multiple ACVRL1 mutations in patients with pulmonary arterial hypertension by targeted exome captureClin Sci (Lond)2016.9.113017):1559~1569

(3) Liu, XuxiaJiang, TengyongPiao, ChunmeiLi, XiaoyanGuo, JunZheng, ShuaiZhang, XiaopingCai, TaoDu, JieScreening Mutations of MYBPC3 in 114 Unrelated Patients with Hypertrophic Cardiomyopathy by Targeted Capture and Next-generation Sequencing.Sci Rep2015.6.19511411

(4) Guo, JunCai, LunJia, LixinLi, XiaoyanXi, XinZheng, ShuaiLiu, XuxiaPiao, ChunmeiLiu, TingtingSun, ZhongshengCai, TaoDu, JieWide mutation spectrum and frequent variant Ala27Thr of FBN1 identified in a large cohort of Chinese patients with sporadic TAAD.Sci Rep2015.01.01513115~13115

(5)Wang, XinguoLiu, XuxiaGe, HailongYang, QingLiu, XiaoliShi, DongmeiZhou, YujiePositive association of coronary calcium detected by computed tomography coronary angiography with periprocedural myocardial infarction.PLos One2013.01.01812):e82835~e82835

(6) Liu, X XLi, S HChen, J ZSun, KWang, X JWang, X GHui, RTEffect of soy isoflavones on blood pressure: a meta-analysis of randomized controlled trials.Nutr Metab Cardiovasc Dis2012.6.01226):463~470

(7) Zheng XX, Xu YL, Li SH, Liu XX, Hui R, Huang XH. Green tea intake lowers fasting serum total and LDL cholesterol in adults: a meta-analysis of 14 randomized controlled trials. Am J Clin Nutr. 2011 Aug; 94(2):601-10.

(8)Li SH, Liu XX, Bai YY, Wang XJ, Sun K, Chen JZ, Hui RT. Effect of oral isoflavone supplementation on vascular endothelial function in postmenopausal women: a meta-analysis of randomized placebo-controlled trials. Am J Clin Nutr. 2010 Feb;91(2):480-6

(9) Liu, XuxiaHuang, HaixiaWang, WeiWang, JunSachs, FrederickNiu, WeizhenStretch-activated potassium channels in hypotonically induced blebs of atrial myocytes.J Membr Biol2008.01.012261-3):17~25.

3-5. 授权发明专利

杜杰; 朴春梅; 顾虹; 朱燕; 习昕; 刘旭霞; 李晓燕; 郭俊, 肺动脉高压致病基因ACVRL1突变位点及其应用, 2017.11. 3, 中国, ZL201510082418.6