刘旭霞
2021-12-28
3-1. 教育经历:
1997-2002,山东泰山医学院,临床医学,本科
2002-2005,首都医科大学,生理学,硕士
2005-2008,首都医科大学,内科学(心血管病),博士
3-2. 工作经历:
2008-2010,阜外心血管病医院,博士后
2010-2016,首都医科大学附属北京安贞医院/北京市心肺血管疾病研究所,助理研究员
2016-至今,首都医科大学附属北京安贞医院/北京市心肺血管疾病研究所,副研究员
3-3. 主持或参加科研项目(课题)及人才计划项目情况:
1. 国家自然科学基金中加合作项目《欧洲和亚洲人群主动脉瓣钙化狭窄的遗传基础》(2019/01-2021/12),参与
2. 北京自然科学基金面上项目,7162032,利用患者特异的诱导多潜能干细胞研究扩张型心肌病猝死家系,2016/01-2018/12,主持
3. 国家自然科学基金青年项目,81401780,糖皮质激素通过调控成纤维/脂肪祖细胞的分化导致2型糖尿病小鼠骨骼肌内脂肪沉积的机制研究,2015/01-2017/12,参与
4. 国家自然科学基金青年项目,81300074,利用外显子捕获测序技术鉴定肥厚型心肌病新致病突变的研究,2014/01-2016/12,主持
5. 国家自然科学基金青年项目,81100144,趋化因子配体16(CXCL16)导致心梗后炎症及心脏损伤的机制研究,2012/01-2015/12,参与
3-4.代表性论著
(1) Zheng S#, Piao C, Liu Y, Liu X, Liu T, Zhang X, Ren J, Liu Y, Zhu B, Du J*. Glycan Biosynthesis Ability of Gut Microbiota Increased in Primary Hypertension Patients Taking Antihypertension Medications and Potentially Promoted by Macrophage-Adenosine Monophosphate-Activated Protein Kinase.Front Microbiol. 2021 Nov 4;12:719599.
(2) Piao C,Zhu Y,Zhang C,Xi X,Liu X,Zheng S,Li X,Guo J,Jia L,Nakanishi T,Cai T,Gu H,Du J,Identification of multiple ACVRL1 mutations in patients with pulmonary arterial hypertension by targeted exome capture,Clin Sci (Lond),2016.9.1,130(17):1559~1569
(3) Liu, Xuxia,Jiang, Tengyong,Piao, Chunmei,Li, Xiaoyan,Guo, Jun,Zheng, Shuai,Zhang, Xiaoping,Cai, Tao,Du, Jie,Screening Mutations of MYBPC3 in 114 Unrelated Patients with Hypertrophic Cardiomyopathy by Targeted Capture and Next-generation Sequencing.,Sci Rep,2015.6.19,5(11411)
(4) Guo, Jun,Cai, Lun,Jia, Lixin,Li, Xiaoyan,Xi, Xin,Zheng, Shuai,Liu, Xuxia,Piao, Chunmei,Liu, Tingting,Sun, Zhongsheng,Cai, Tao,Du, Jie,Wide mutation spectrum and frequent variant Ala27Thr of FBN1 identified in a large cohort of Chinese patients with sporadic TAAD.,Sci Rep,2015.01.01,5:13115~13115
(5)Wang, Xinguo,Liu, Xuxia,Ge, Hailong,Yang, Qing,Liu, Xiaoli,Shi, Dongmei,Zhou, Yujie,Positive association of coronary calcium detected by computed tomography coronary angiography with periprocedural myocardial infarction.,PLos One,2013.01.01,8(12):e82835~e82835
(6) Liu, X X,Li, S H,Chen, J Z,Sun, K,Wang, X J,Wang, X G,Hui, RT,Effect of soy isoflavones on blood pressure: a meta-analysis of randomized controlled trials.,Nutr Metab Cardiovasc Dis,2012.6.01,22(6):463~470
(7) Zheng XX, Xu YL, Li SH, Liu XX, Hui R, Huang XH. Green tea intake lowers fasting serum total and LDL cholesterol in adults: a meta-analysis of 14 randomized controlled trials. Am J Clin Nutr. 2011 Aug; 94(2):601-10.
(8)Li SH, Liu XX, Bai YY, Wang XJ, Sun K, Chen JZ, Hui RT. Effect of oral isoflavone supplementation on vascular endothelial function in postmenopausal women: a meta-analysis of randomized placebo-controlled trials. Am J Clin Nutr. 2010 Feb;91(2):480-6
(9) Liu, Xuxia,Huang, Haixia,Wang, Wei,Wang, Jun,Sachs, Frederick,Niu, Weizhen,Stretch-activated potassium channels in hypotonically induced blebs of atrial myocytes.,J Membr Biol,2008.01.01,226(1-3):17~25.
3-5. 授权发明专利
杜杰; 朴春梅; 顾虹; 朱燕; 习昕; 刘旭霞; 李晓燕; 郭俊, 肺动脉高压致病基因ACVRL1突变位点及其应用, 2017.11. 3, 中国, ZL201510082418.6